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The gray-zone prostate-specific antigen (PSA) range is accepted to be 4-10 ng/ml and is considered to vary according to age. We aimed to investigate whether fusion prostate biopsy (FPB), which has been reported to have relatively higher cancer detection rates, has an effect on gray-zone PSA cut-off value.
There is no consensus in the literature regarding the normal PSA range. However, the upper limit for PSA is often accepted to be 2.5 or 4.0 ng/ml, and it is considered to vary according to age [4-5]. The same situation is valid for the definition of gray-zone PSA. Although some studies suggest that the gray-zone PSA range may show regional and ethnic variation, some other studies have proposed an upper limit of 10 ng/ml for gray-zone PSA [6-9]. 781b155fdc